By Ahmed Abdelsalam
US Health Secretary Robert F Kennedy Jr. has announced plans to loosen restrictions on six unapproved peptides, allowing compounding pharmacies to prepare them for patients. The proposal was published in the Federal Register on Wednesday and marks an unusual move originating from the health secretary's office rather than the Food and Drug Administration (FDA).
Plan Details
The peptides covered by the plan include BPC-157, TB-500, KPV, MOTS-c, and Semax. Compounding pharmacies would be permitted to mix these substances into medications. After official publication later this week, a two-week public comment period will follow.
FDA Panel Vote and Kennedy's Stance
An FDA advisory panel voted in July to loosen restrictions on the six peptides, though FDA staff members recommended against the change. Kennedy has described himself as a "big fan" of the drugs and previously vowed to ease restrictions after the Biden administration cracked down on the growing industry.
What Are Peptides?
Peptides are short chains of amino acids that act as cellular messengers, playing roles in skin health, immune function, and hormone regulation. Insulin, a peptide hormone, has been used to treat diabetes for over a century. However, unregulated injectable peptides have surged in popularity alongside the rise of GLP-1 weight-loss drugs.
Online Popularity and Expert Concerns
Online influencers market peptides in "stacks" for unproven uses such as anti-aging, muscle building, and skin improvement. The trend has gained traction among teenagers on TikTok, particularly boys, under movements known as "biohacking" and "looksmaxxing." Health experts warn of a lack of human clinical trials and unknown long-term effects.
